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Taken together, we propose that chronic GSH depletion induces redox activation of the AMPK pathway that may serve as the central link triggering mechanisms that prevent alcohol-induced liver injury (as illustrated in Fig

Eurasian J

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Rodriguez et al

Subsequent sex comparison analysis showed that compared to that in healthy men, healthy women had higher GSTA4 methylation levels CpG1 ( p = .004, Table 5), CpG2 ( p = .024), CpG3 ( p = .042), CpG4 ( p = .041), CpG6 ( p = .038), CpG8 ( p = .035), CpG9 ( p = .02), mean methylation levels of the nine CpG sites ( p = .019)