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The AKT can phosphorylate MDM2 on ser166/186, which activates MDM2 to decrease p53 levels and activity, and thus forms a negative feedback loop with p53 51

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eligibility for compounding (regulatory status remains in flux through 2026) is not the same as approval [10]

Splitting your protein target across smaller, more frequent meals or snacks throughout the day is a reasonable way to still hit your overall needs without forcing a large meal