Liver dysfunction does not explain every mood or cognitive symptom, but oxidative stress, altered medication metabolism, gut-derived inflammation, ammonia, copper imbalance, low glutathione and impaired methylation may reduce neurological resilience in selected patients
However, current studies targeting Gln transporters for the treatment of DSMTs remain limited, especially clinical data
Malondialdehyde (MDA) and 4-hydroxy-nonenal (4-HNE) are the major products of lipid peroxidation (65)
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doi: 10.1002/jps.2600520809, 31