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Esses compostos experimentais representam uma aposta perigosa para a sade a longo prazo

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Kaji and collaborators demonstrated that sitagliptin markedly inhibits liver fibrosis development in rats via suppression of hepatic stellate cell proliferation and collagen synthesis (158)

Moreover, during early postnatal development, trigeminal neurons display differential expression of the NMDA receptor subunits NR2A and NR2B, with a developmental shift from NR2B to NR2A dominance that dictates excitatory postsynaptic current kinetics and synaptic plasticity rules (Turman et al., 1999