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Cellular senescence: a translational perspective

Berberine is one of the betterstudied supplements with multiple human trials showing glucoselowering effects

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It can also enhance intestinal barrier function and reduce inflammation in high-fat diet-fed mice by suppressing the TLR4/NF-B pathway, and by increasing the Bacteroidetes / Firmicutes ratio while reducing the abundance of genera such as Alistipes , Lachnospiraceae_NK4A136_group , and Romboutsia