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81,82 Despite the limitations of the currently available knowledge in the literature from Arab countries, the number of included publications has notably increased since 2018, highlighting the growing positive clinical attitudes toward treating obesity

Concomitant use of phentermine and topiramate extended-release capsules and a carbonic anhydrase inhibitor may increase the severity of metabolic acidosis and may also increase the risk of kidney stone formation [see Warnings and Precautions (5.10)]

Serum angiopoietin-like 4 protein levels and expression in adipose tissue are inversely correlated with obesity in monozygotic twins

For example, people with a history of certain medical conditions, such as thyroid cancer or pancreatitis, may need to avoid this medication