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Due to the drug's ability to regulate reward and motivation, it has also been extended to people suffering from obesity and increased body mass, who often crave high calorie foods in an addictive manner

Electronic supplementary material 13058_2008_2172_MOESM1_ESM.ppt (download PPT Additional file 1: Powerpoint file showing the growth inhibitory effect of buthionine sulfoximine (BSO) and 17-estradiol (E 2 ) in MCF-7:2A cells is reversed by the antiestrogen 4-hydroxytamoxifen (4-OHT)

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inhibit the activity of cyclooxygenase-2 enzyme, reducing the production of pro-inflammatory and pro-oxidant prostaglandins along with lipid peroxidation

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