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Unlike GLP-1 agonists, metformin works primarily on existing insulin pathways rather than triggering new hormonal signals

End-stage renal disease risk in lupus nephritis may also be mitigated by GLP-1 agonism, she added

The count data were filtered to remove genes with low expression, transformed using the variance stabilizing transformation from the DESeq2 package (51), and then batch corrected using ComBat (52)