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After 14 days, the mice were sacrificed, and their major organs and tissues were analyzed with a hematoxylin and eosin (H&E) stain (Supplementary Fig

1,2 It is coabsorbed with intrinsic factor, a product of the stomach's parietal cells, in the terminal ileum after being extracted by gastric acid 1,2 (Figure 1 3 )

Youll start on a low dose of allopurinol, which can be gradually increased until you are on the right dose