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Vial fell or was shaken accidentally If a reconstituted vial was shaken vigorously (dropped, thrown in a bag, held by a toddler), some peptide degradation may have occurred

You could be injecting B12 religiously while your cells are basically starving

Use only the diluent specified by the manufacturer or dispensing pharmacy. How is peptide contamination reduced during reconstitution and handling

doi: 10.3389/fbioe.2021.643722 Summary Keywords antifungal, alginate oligosaccharide, nystatin, Candida spp., biofilm Citation Powell LC, Adams JYM, Quoraishi S, Py C, Oger A, Gazze SA, Francis LW, von Ruhland C, Owens D, Rye PD, Hill KE, Pritchard MF and Thomas DW (2023) Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms