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Herken H, UZ E, Ozyurt H, Sgt S, Virit O, Akyol O

Adv Gerntol 2012;25:718-728

GSSG concentration and GSSG/GSH ratios in the skeletal muscle of Phase-I HSB were reduced ( P 0.05) in concentrations of GSH or total glutathione in the muscle was detected among all treatment groups (Table 2)

conducted an in-depth study and reported that FAs participate in the transcription of NLRP3 and Pro-IL-1, promoting the onset of GA inflammation by activating the Toll-like receptor (TLR) pathway in conjunction with MSU ( Thus, TLR2/TLR4 activation promotes the dissociation of the inhibitor of nuclear factor kappa-B (I-B)/NF-B complex through a myeloid differentiation primary response 88-dependent (MyD88) signaling pathway, mediating the nuclear translocation of nuclear factor kappaB (NF-B) and specifically acting on the NLRP3 and IL-1B gene promoter regions

The C-circle assay was performed using qPCR QuantStudio V1.3 software