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Various GLP-1RAs have been demonstrated to have significant benefits in in vitro and in vivo models of neurodegenerative diseases through modulating a variety of pathogenic mechanisms, including neuroinflammation, autophagy, mitochondrial dysfunction, and the abnormal phosphorylation of pathognomonic proteins

Safety notes: Contraindicated in individuals with a personal history of cancer, uncontrolled diabetes, significant cardiovascular disease, or untreated sleep apnea

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Thighs and arms, where smaller pockets of fat may affect overall proportions