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All findings are derived from in vitro cell culture or animal model research

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Neuroimaging, particularly combining structural MRI, functional MRI, and magnetic resonance spectroscopy, has enhanced sensitivity to early alterations in network connectivity, microstructural integrity, and metabolic function, even in AD animal models [600]

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Furthermore, it highlighted a concern based on in vitro and animal data that those with low iodine uptake or compromised thyroid function may increase their risk of developing clinical hypothyroidism with the ingestion of soy-containing foods