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The combination of DNase-I + amikacin resulted in a strong increase in dead biofilm compared to DNase I treatment alone, and the triple therapy combination of GSH + DNase-I + amikacin showed the highest level of biofilm disruption (Figure 3C)

The difference is that the topical claim has supporting human cosmetic studies behind it, while the injectable skin claim has mechanism plus animal data and nothing more

Given that oxidized proteins are prone to degradation (34), we hypothesized GSH depletion could result in a lower level of FASN protein in liver

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Moreover, the mice maintained on a KD presented with a higher number of immune cells and a higher ratio of CD4 + T cells to Tregs, while the functionality of the Tregs was weakened