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The clinical reality of GLP-1 therapy is that most patients plateau between 6 and 18 months

The brain uses about 20% of total energy expenditure and relies heavily on glucose

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The perfusion system (UP-100 universal perfusion system, Hugo Sachs Elektronik, Germany) maintained constant flow of 1 ml/min, perfusion buffer was heated and oxygenated (95% O 2 , 5% CO 2 ) and pressure was monitored throughout the experiment (4050 mmHg)

[1] [2] Hypoglycaemia: If you are also taking insulin or a sulfonylurea, retatrutide may increase the risk of low blood sugar