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Effects of combination therapy on intermediate endpoints and side effects according to meta-analyses of randomized trials We analysed data from 6 meta-analyses (Table 1), which assessed the effect of the combination therapy on HbA1c and body weight

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In addition, the dose and duration of intravenous anesthesia in animal studies are very different from those used in human anesthesia, making it very difficult to generalize findings from animal studies to clinical practice

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