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their under-eye circles disappear, they feel more clear-minded and energetic, and their wrinkles look less intense

This result might be attributable to the small number of patients and the long duration and severity of T2D, as well as the presence of comorbidities

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161,168 The most significant pharmacokinetic alterations were reported following the administration of a single 5 mg dose of tirzepatide, with the C max and AUC values of ethinylestradiol decreasing by 59% and 21%, respectively, and those of norelgestromin by 55% and 22%, respectively (Table 4)