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Cells were then incubated with 0.15 g/ml DAPI for 1 min, washed three times with PBS, mounted with fluorescence mounting medium (9 ml of glycerol [BP229-1

Excess iron is associated with the development of cancer, mainly because of its pro-oxidant effects, which can contribute to DNA damage and promotion of oncogenesis

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse

Furthermore, the precise molecular mechanisms underlying antioxidant therapy, the optimal timing for intervention, and the interactions between antioxidants and existing hormonal or anti-inflammatory treatments remain to be elucidated

M., Setti, T., Mosaner, T., Simplicio, C