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The removal process typically requires multiple sessions over several months to a year, depending on the type and depth of the pigment

Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is considered as effective as intramuscular administration for correcting anemia and neurologic symptoms Despite many studies suggesting oral administration of vitamin B 12 to be easy, effective and less costly than intramuscular administration, debate surrounds the effectiveness of the oral route

Its also a vital component of several important liver functions and plays a large role in managing mitochondrial function and maintaining DNA

Nakano T, Inoue I, Alpers DH et al (2009) Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration

The need to use different laboratory markers of vitamin B12 to aid in diagnosis stresses the importance of making these markers widely available and affordable, which is not the case in many countries