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Namely, the retina and the brain share many supporting functional and structural similarities [138], and as one of the longest central nerves, the optic nerve connects the retina to the thalamic brain nuclei [31]
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The proposed mechanism involves controlling glutamate release in the synaptic cleft, modulating NMDA receptor stimulation, affecting excitatory amino acid transporter (EAAT)-mediated reuptake, and maintaining the glutamate/glutamine cycle within astrocytes
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