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Studies with follow-up of less than 1 year In a case series of 38 patients with a mean follow-up period after PRP therapy of 75.92 31.7 days, Medina-Porqueres et al

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Subsequently, the NTD translocates to the PM and oligomerizes to form large membrane pores that allow the release of cellular contents, including the pro-inflammatory cytokines interleukin-1 and -18 and drive swelling and membrane rupture