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Mediterranean diet and age-related cognitive decline: a randomized clinical trial

Nat Cell Biol 2016;18:886-96

Ferrostatin-1 (Fer-1) alleviated TGF--induced ferroptosis in DKD patients, suggesting that renal tubular cell death is related to ferroptosis and that repressing ferroptosis could potentially serve as a therapeutic strategy for DKD [148]

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SFN treatment also reduced the activation of STAT3 and NF-B pathways and downregulated pro-inflammatory cytokines IL-1, IL-6, and CCL2