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Laboratory investigations explore how different types of senescent cells contribute to various aging phenotypes, while the peptide's selectivity enables researchers to test causal relationships between senescent cell burden and age-related functional decline

The extensive contact area between peptide ligands and the GLP-1 receptor, spanning both the ECD and TMD and involving dozens of intermolecular contacts across a surface area exceeding 1,000 square angstroms, seemed to require the structural complexity that only a peptide could provide

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