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these measurements were repeated every 4 weeks until week 20, and every 8 weeks thereafter, until week 100 and week 104 (within 3 days either side of scheduled visit day)

10.1159/000438601 25 BissingerR.ArtuncF.QadriS

(2018) 13:e0196716

Disease stage and remaining tissue considerations Early disease with substantial viable tissue: Maximum benefit from protective mechanisms