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N Engl J Med (1980) 302:313.10.1056/nejm198001033020105 68 KibirigeDLuzindaKSsekitolekoR

Endothelial markers are associated with pancreatic necrosis and overall prognosis in acute pancreatitis: a preliminary cohort study

The selectivity for beta-3 receptors explains the favorable safety profile compared to non-selective beta agonists that cause cardiovascular stimulation and other systemic effects

But more than three decades ago, when Habener, Massachusetts General Hospital and Harvard Medical School investigator emeritus, set up an experiment that helped lead to the discovery, this outcome was far from clear

observed reversal of diastolic ventricular dysfunction in a rat model due DPP4 inhibition, via local actions on angiogenesis and inotropic effects [76]