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Yes, B12 shots are key for treating neurological symptoms caused by B12 deficiency

The classic symptoms of B12 deficiency are persistent fatigue, tingling or numbness in the hands and feet, problems with memory and concentration, mouth ulcers, a sore red tongue, and pale or yellow-tinged skin

There are exceptions to this but in general it is left to Pharmaceutical companies to develop medicines that can be used to treat diseases like Pernicious Anaemia

Common research community cycles run 8 to 12 weeks on, followed by 4 to 6 weeks off

Additionally, if they have parts of the inflamed terminal ileum removed, the risk for malabsorption is increased