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Injection: Clinical Comparison (2026) The Obesity Society Evidence-Based Obesity Treatment Guidelines

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People with BMIs of 35 or higher automatically qualify

Wash your hands thoroughly and select an injection site, rotating sites with each dose to prevent lipohypertrophy (fatty lumps under the skin) or lipoatrophy (loss of fatty tissue)

But, if Reddit is any indication, plenty of women do report period changes on GLP-1s, including: Changes in bleeding or PMS symptoms Cycle regularity A stop to their periods Heres a sampling of the Reddit comments youll find on the topic: I have PCOS and haven't had a period in something like 5 years