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10.1016/j.pbi.2015.11.009 Curr

Group 2 (non-diabetic autoantibody-negative cases) In cases 6289, 6160, 6055 and 6229, many insulin cells showed weak GPX1 staining while in case 6178, 97% of such cells were negative with only 24% of glucagon cells with moderate to strong staining

Yet beneath the extraordinary clinical results and the unprecedented commercial momentum lies a fundamental contradiction that the industry has largely avoided confronting: despite the breadth of physiological systems these agents appear to influence, we still lack a unified and reproducible mechanistic model capable of explaining their full biological scope

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[2] Oxidative phase of the pentose phosphate pathway The oxidative phase of the pentose phosphate pathway consists of two irreversible oxidation reactions , the first and third steps, and one hydrolysis