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Activating these receptors reduces what many patients describe as "food noise," the persistent, intrusive preoccupation with food and eating that makes sustained caloric restriction so difficult to maintain through willpower alone [7]

These fluctuations can increase oil production, clog pores, and lead to inflammation and breakouts

[1] This is not a formal contraindication, but rather a precautionary recommendation based on limited safety data in this population

Some individuals may also experience injection-site reactions or gallbladder-related symptoms 7