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She likens the phenomenon to insulin resistance, which is still not fully understood decades after its discovery

SARS-CoV-2 infection dysregulates host iron (Fe)-redox homeostasis (Fe-R-H): role of Fe-redox regulators, ferroptosis inhibitors, anticoagulants, and iron-chelators in COVID-19 control

albicans can finely regulate multiple iron uptake pathways such as high-affinity iron reduction systems and heme uptake through mechanisms such as the Sef1-Sfu1-Hap43 regulatory circuit and the iron-sulfur cluster assembly system, thereby promoting invasive and morphological transformation processes related to virulence, and accelerating the progression of infection (Zheng et al., 2025)