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10.1227/NEU.0000000000001264 Neurosurgery 51 ZhuH.ZhangY.ShiZ.LuD.LiT.DingY.et al (2016)

The drug shows promise in addressing obesity by potentially offering a more effective treatment with lower dosages and fewer side effects

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Coya said the trial met its primary endpoint for safety and secondary endpoint for regulatory T cell (Treg) cell population enhancement, with no off-target effects on T effector lymphocytes, providing further evidence of target engagement in 22 patients dosed with five days of LD IL-2 (106 IU/day) or placebo every four weeks for 21 weeks