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Persistent symptoms lasting over 72 hours, inability to keep fluids down for 24 hours, or signs of dehydration (dark urine, dizziness) require immediate medical evaluation for underlying conditions

Tissue homogenization: Frozen tissue of brain was homogenized in 9 volumes of ice-cold tissue lysis buffer containing 150 mM sodium chloride, 1.0% NP-40, 50 mM Tris, pH 8.0 and 1 mM PMSF (phenylmethane sulfonylfluoride) with protease inhibitors (Sigma, Singapore)

People tend to lose more weight with Qsymia than with topiramate alone

It is a once-weekly injection that can be self-administered at home

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