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Targeting specific signaling pathways, such as JAK/STAT, PI3K/AKT, and NF-B, which regulate TAM polarization, along with innovative strategies like nanocarriers, exosomes, and CAR-macrophage therapy, could significantly improve the efficacy of cancer treatments, particularly in solid tumors where immunosuppression is a major challenge (155)

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Because of this, more patients may find themselves in the position to participate in a clinical trial themselves, which in turn can come with many questions about safety and benefit

[11] Renal function should be checked if dehydration is suspected

Or, double-check the instructions and make sure you werent doing something wrong