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doi: 10.3390/nu17010067

Mounjaro (tirzepatide) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist (RA) that was recently approved by the FDA for the treatment of type 2 diabetes

doi: 10.3390/ijms24076794 372 AbdelhamidMCountsSEZhouCHidaHKimJIMichikawaMet al

In Phase 2 trial data, the most commonly reported adverse effects included: Nausea (reported in a significant proportion of participants, particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite (which, whilst contributing to weight loss, can occasionally be excessive) These effects were generally described as mild to moderate in severity and tended to diminish over time as the body adjusted to the medication

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