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Doses greatly exceeding the nutritional requirements (for example, hundreds of milligrams daily) have not been studied in randomized trials for safety, so one should avoid mega doses in pregnancy unless treating a specific condition (such as pyridoxine-responsive seizures) under careful supervision

Ask if your condition can be treated in other ways

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Your doctor might suggest protein supplementation or dietary changes rather than attributing the changes to medication side effects that would require a dose reduction

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