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The CGRD is the largest multi-institutional electronic medical record (EMR) database in Taiwan [21], including 2 medical centers and five general hospitals, and information on more than 11 million patients from 2001 to 2019

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AKAP11 binds to vesicles, peroxisomes and centrosomes and forms signalling hubs at these intracellular locations with PKA, GSK3 and Ras GTPase-activating-like protein-1 (IQGAP1), all of which directly regulate CaMKK2 activity [35, 40, 64]