Cardiometabolic complications are inside the indication, not adjacent to it
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For example, obesity and visceral fat accumulation showed positive association with DPN, and insulin resistance can be involved in this pathophysiology observed in T2DM [11]
5 Key mediators in the immune regulation of the gut-lung axis: PAMPs and DAMPs Pattern recognition receptors (PRRs) serve as key mediators in the immune regulation of the gut-lung axis by recognizing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) (138)
Crosstalk between Microbiota-Derived Short-Chain fatty acids and intestinal epithelial HIF augments tissue barrier function