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2005;4:CD004227

Proteomic analysis in synovial fluid The protein composition in synovial fluid reflects the state of the intra-articular environment, and proteomic analysis can identify biomarkers associated with OA in synovial fluid

Chronic pain can be exacerbated by stress, anxiety, and depression

These findings suggest a possible modulatory effect on HPO signaling, potentially mediated by anti-inflammatory pathways, although causality and long-term reproductive implications remain uncertain

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