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Perturbations in the gut microbiota expose the intestine to inflammatory and genotoxic metabolites such as secondary bile salts, trimethylamine N-oxide, hydrogen sulfide, heme, nitrosamines, heterocyclic amines, and polyaromatic hydrocarbons

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Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart

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