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doi: 10.3389/fphar.2025.1595160 Received 17 March 2025 Accepted 28 April 2025 Published 19 May 2025 Volume 16 - 2025 Edited by Chunrun Qu, University of Oxford, United Kingdom Reviewed by Ianis Kevyn tefan Boboc, University of Medicine and Pharmacy of Craiova, Romania Madalina Iuliana Musat, University of Medicine and Pharmacy of Craiova, Romania Peng Teng, Zhejiang University, China Updates Copyright 2025 Gao, Sai, Shang, Zhong, Kong, Liu and Wang

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There are numerous physical features and congenital conditions specific to DS, resulting from overexpression of genes caused by the extra chromosome presented in Table 1

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