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These effects result in increased glucose uptake and metabolism in adipose tissue, which is required for triglyceride synthesis, and the uptake and storage of glucose as glycogen in skeletal muscle

Receptor Downregulation Findings and Study Design Implications A well-documented finding in the research literature is that continuous IGF-1 receptor activation leads to receptor downregulation after approximately four to six weeks, reducing cellular responsiveness to further stimulation

Vibet S, Goupille C, Bougnoux P, Steghens JP, Gore J, Maheo K

doi: 10.2174/13816128130111

In particular, CJC-1295 has been demonstrated to preserve growth hormones physiologic effects on hyperplasia, hypertrophy, bone density, blood sugar, fat metabolism, protein synthesis, and myocardial (heart cell) function