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Some patients who stopped smoking may have been experiencing symptoms of nicotine withdrawal, including depressed mood

Nicotine is a vasoconstrictor, which means it narrows/constricts the blood vessels in the gums

Individuals experience irritability, anxiety, and increased appetite when they try to quit

First, the bias covariates used, although carefully extracted and evaluated, were based on observable study characteristics and thus may not fully capture unobserved characteristics such as study quality or context, which might be major sources of bias

By informing your loved ones about your decision to quit, you not only gain their encouragement but also their help in keeping you accountable