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The benefits of enemas on rheumatoid arthritis and cancer have mostly been tested in small, uncontrolled studies, one of which also used chemotherapy

Owing to the lack of high-quality cell-type-specific protein concentration data for young and old rodents, we relied on data on RNA levels to derive the concentrations of enzymes and transporters, with scaling in the aging group based on the assumption that changes in RNA directly affect enzyme concentrations (61)

Dose-Response Relationships In animal stroke models, gene expression changes occurred 1-24 hours post-administration, but whether similar timing applies to psychiatric effects is unknown