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A meta-analysis of randomized controlled trials (RCTs) involving nonpharmacological interventions to reduce body weight, based on data from twenty-five trials and 4874 participants, reported that each kilogram of weight reduction may result in at least 1 mmHg reduction in BP [9]

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Conversely, some dermatoscopic patterns argue against amelanotic melanoma: a symmetric pigmentation pattern, irregular and multiple blue-gray globules, multiple milia-like cysts, and predominantly comma vessels [38]