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22 In the liver of WT mice, phosphorylation of JNK which is activated by TNF- was increased by Con A administration, whereas its phosphorylation did not increase in the liver of Gpx1 KO mice injected with Con A (Figure 3b)

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The trial lasted 68 weeks and included 3417 individuals who were randomized to either CagriSema, its individual components or placebo [125]