Jay Campbell Peptide Educator & Author Eighteen peptides with syringe-level dosing in a single document
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(3) V Susi, G Masirevi, and S Toti (1987) The effects of delta-sleep-inducing peptide (DSIP) on wakefulness and sleep patterns in the cat Brain Research, 1987 Jun 30, Volume 414 (Issue 2), Pages 262-70
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A second, more subtle reason is that the sp3 hybridized carbon on the ring junction (adjacent to the nitrogen) imparts a slight pucker to the nitrogen, so that orbital overlap is even more difficult than in a linear amide