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More specifically, both RCTs with paired liver biopsies showed improvement in hepatic steatosis and inflammation, but not fibrosis, after treatment with liraglutide or semaglutide

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Tight junctions consist of four unique families of transmembrane proteins including occludin, claudins, junctional adhesion molecules, and tricellulin, and are considered one of the principal determinants of mucosal permeability (Fig