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Description

The ethnomedical approach integrating natural remedies, dietary guidelines, and lifestyle modifications, induce a symbiotic relationship between individuals and their environment (232)

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Studies in animal models, such as hypertensive mice and rats and apolipoprotein E-deficient mice, have demonstrated that oxidative depletion of BH 4 leads to increased eNOS-derived superoxide, which impairs vasorelaxation (Hong et al., 2001

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