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Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma

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Researchers continue to investigate how the combined biological activities represented in KLOW influence collagen biology, connective tissue maintenance, epithelial integrity, angiogenesis, and the complex signaling pathways involved in normal tissue homeostasis

Interestingly, higher plasma levels of cystine indicated a high probability of response in patients with non-small cell lung cancer before and after treatment with the immune checkpoint inhibitor nivolumab, which targets programmed cell death protein 1