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Health Canada approval will follow FDA decisions, typically with several months lag time

When the quantity of bicarbonate ions is insufficient to maintain normal pH, the body is capable of mobilizing alkaline calcium salts from bone in order to neutralize acids consumed in the diet and generated by metabolism (42)

The spinal cord was carefully removed by laminectomy, postfixed for 4 h in 4% PFA and transferred into 30% sucrose overnight for cryoprotection

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Cultures were maintained in a humidified atmosphere of 5% CO 2 at 37C for 24 h and then incubated for the next 24-h period in DMEM-10% HS additionally containing recombinant HGF that was treated with peroxynitrite with or without trisulfide pre-treatment (see Figure 1d,f)